Standard Extract Series

St.Johns Wort Extract

Latin Name:Hypericum perforatum
Active Ingredient:Hypericins/Hyperforin
CAS No:548-04-9/118-34-3
Specification:0.3%Hypericins
MOQ:1kg
Lead Time:Within 7days after confirming order

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St. John's Wort Extract Information:

St. John's Wort (Hypericum perforatum) is native to and relatively widespread in the temperate climes of Europe, western Asia, and North Africa. It was also introduced to other temperate climes. It prefers sunny locations on dry, limy or primary rocky soils and is found on fallow land, the edges of meadows and forests, walls, and paths up to an altitude of 1500 metres.

Specification: 0.3%, 1% Hypericins Test by UV
                        3.0% Hyperforin Test by HPLC
Molecular Formula: C30H16O8
Molecular Mass: 504.44
CAS NO.: 118-34-3
Constitutional Formula

Ingredients:
Hypericin Pseudohypericin Protohypericin Protopseudohypericin Kampferol Luteolin Hyperforin Adhyperforin

Benefits:

St. John's wort has been used for centuries to treat mental disorders and nerve pain.
In ancient times, herbalists wrote about its use as a sedative and a treatment for malaria, as well as a balm for wounds, burns, and insect bites.

Today, St. John's wort is used by some for depression, anxiety, and/or sleep disorders.
1.Depression -- St. John's wort is helpful in the therapy of mild to moderate depression with fewer side effects than conventional pharmaceutical antidepressants. The effect of St. John's wort may be noticed the first day, but often it takes a few days or weeks for the full benefits of St. John's wort to occur. Some studies indicate that St. John's wort may be as good an antidepressant as some of the SSRIs such as Prozac and Zoloft. A 6 week double blind study using a combination of St. John's wort, valenian, and passion flower found the combination to be effective in treating mild depression. The dosage used was 360 mg for St. John's wort, 160 mg for valerian, and 190 for passionflower taken once daily. Other supplements used for depression include 5-HTP which is a serotonin precursor, SAM-e which is very potent and needs to be used in low dosages, and Tryptophan, which converts into serotonin. If your doctor approves, you can take one capsule of St. John's wort in the morning and half a capsule of a 50 mg 5 HTP in the afternoon or evening. Some people find the low dose combination of 5 HTP and St. John's wort to be helpful. 
2.PMS -- St. John's wort has been found to be partially helpful in treating PMS.
3.Weight loss -- St. john's wort may be helpful in appetite control when combined with other natural supplements.
4.Somatoform disorders


What the Science Says:

There is some scientific evidence that St. John's wort is useful for treating mild to moderate depression.
However, two large studies, one sponsored by NCCAM, showed that the herb was no more effective than placebo in treating major depression of moderate severity.
NCCAM is studying the use of St. John's wort in a wider spectrum of mood disorders, including minor depression.

Side Effects and Cautions:

St. John's wort may cause increased sensitivity to sunlight. Other side effects can include anxiety, dry mouth, dizziness, gastrointestinal symptoms, fatigue, headache, or sexual dysfunction.

Research shows that St. John's wort interacts with some drugs. The herb affects the way the body processes or breaks down many drugs; in some cases, it may speed or slow a drug's breakdown. Drugs that can be affected include:

Indinavir and possibly other drugs used to control HIV infection

Irinotecan and possibly other drugs used to treat cancer
Cyclosporine, which prevents the body from rejecting transplanted organs
Digoxin, which strengthens heart muscle contractions
Warfarin and related anticoagulants
Birth control pills

Antidepressants:

When combined with certain antidepressants, St. John's wort may increase side effects such as nausea, anxiety, headache, and confusion. St. John's wort is not a proven therapy for depression. If depression is not adequately treated, it can become severe. Anyone who may have depression should see a health care provider. There are effective proven therapies available. It is important to inform your health care providers about any herb or dietary supplementA product that contains vitamins,minerals, herbs or other botanicals, amino acids, enzymes, and/or other ingredients intended to supplement the diet.

The U.S. Food and Drug Administration has special labeling requirements for dietary supplements and treats them as foods, not drugs. you are using, including St. John's wort. This helps to ensure safe and coordinated care.

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