Artemisia Annua Extract/

Latin Name:Artemisia annua L/Artemisia Apiacea
Active Ingredient:Arteannuin
CAS No:207446-89-7
Specification:98%,99% By HPLC
MOQ:1kg
Lead Time:Within 7days after confirming order

Artemisia Extract Information:

Name of Product: Sweet Wormwood Herb Extract/Artemisia Apiacea Extract
Active Ingredients: Artemisinin
Specification: HPLC 98%, 99% or Extract Ratio 10:1

Artemisinin is mainly used in controlling of vivax malaria and falciparum malaria symptom, as well as treatment of chloroquine-resistant strain of insect. It can also be used to treat dangerous falciparum malaria, be used for treatment of systemic lupus erythematosus and discoid lupus erythematosus.

Active Ingredient:Artemisinin
CAS No.: 63968-64-9
Molecular formula : C15H22O5

Active Ingredient :Dihydroartemisinin (DHA, Dihydroqinghaosu )
Chemical Name: (3R,5aS,6R,8aS,9R,12S,12aR)-decahydro-3,6,9-trimethyl-3,12- epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol
Cas No.: 71939-50-9
Molecular Formula: C15H24O5
Mol. Wt.:284.34806

Active Ingredient :Artesunate (AS)
Cas No.: 83507-69-1, 80155-81-3 (sodium salt)
Molecular Formula: C19H28O8
Mol. Wt.: 384.421

Active Ingredient :Artemether (It is an ether derivative of artemisinin.)
Cas No.: 71963-77-4
Molecular Formula: C16H26O5
Mol. Wt.: 298.374

Description:

Dihydroartemisinin (or dihydroqinghaosu) is a drug used to treat malaria. Dihydroartemisinin is the active metabolite of all artemisinin compounds (artemisinin, artesunate, artemether, etc.) and is also available as a drug in itself.

Artesunate is prepared from dihydroartemisinin (DHA) by reacting it with succinic acid anhydride in basic medium.

Artesunate is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection. It is sometimes abbreviated AS.

Artemether is an ether derivative of artemisinin. It is an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria.

The Artemisinin and its derivatives are derived from the leaf and the upper portions of Arteminsia annua L.

Benefits:
1.Parasite treatment
2.Malaria treatment
3.Cancer treatment (such as be of selectively toxic to some Breast Cancer, Prostate Cancer, Leukemia, and other cancer cells)

Mechanism:
The proposed mechanism of action of artemisinin involves cleavage of endoperoxide bridges by iron producing free radicals (hypervalent iron-oxo species, epoxides, aldehydes, and dicarbonyl compounds) which damage biological macromolecules causing oxidative stress in the cells of the parasite.Malaria is caused by the Apicomplexan, Plasmodium falciparum, which largely resides in red blood cells and itself contains iron-rich heme-groups (in the from of hemozoin).

Safety:
Artemisinin is safe. Well-documented clinical uses of Artemisinin and derivatives have shown few insignificant side effects.

Dosage:
1.For malaria, the typical dose is 3000 mg administered over a 3 to 5 day period.
2.For cancer, the typical dose is 200mg-1000mg per day
3.Consult physicians for different condition specifics.