Feverfew Extract/Parthenolide

Latin Name:Tanacetum parthenium L.
Active Ingredient:Parthenolide
CAS No:20554-84-1
Specification:0.2%-3%Parthenolide HPLC
MOQ:1kg
Lead Time:Within 7days after confirming order

Feverfew Extract
Latin Name:Tanacetum parthenium L.
Active Ingredient:Parthenolide
CAS No:20554-84-1
Specification:0.2%, 0.3%, 0.4%, 0.5%, 0.8%, 1.0%, 1.2%, 3% Parthenolide HPLC
MOQ:1kg
Lead Time:Within 7days after confirming order

Feverfew Extract Information:
Feverfew extract is a liquid or dry dietary supplement made from the leaves of the feverfew, or Tanacetum parthenium plant.It is a brown powder.
Part used: Whole aerial parts  
CAS No:20554-84-1
Active Ingredients:Parthenolide                      
Specification:0.2%-3%Parthenolide HPLC
Packaging:25KG per drum
Storage:Store in cool, dry place.

History:

Feverfew (Tanacetum parthenium), a member of the sunflower family, has been used for centuries in European folk medicine as a remedy for headaches, arthritis, and fevers. The name feverfew comes from a Latin word meaning "fever reducer."Feverfew is used most often today to treat migraine headaches.

Extract the leaves of the plant are dissolved in a liquid base of glycerol, alcohol or water to make the extract.Making feverfew extract a concentrated form of this herbal supplement. You can add feverfew extract to water, juice or tea or take it on its own orally.

Benefits:

Feverfew is a member of the daisy family. Feverfew products usually consist of dried feverfew leaves, but all parts of the plant that grow above ground may also be used for medicinal purposes. It has been used in traditional medicine as far back as the 1st century for inflammatory conditions and to prevent the occurrence of migraine headaches. It has been used for reducing fever, for treating headaches, fevers, arthritis and digestive problems. Feverfew is also used to treat menstrual irregularities, labor difficulties, skin conditions, stomach aches, and asthma. Feverfew may also have GABAergic effects.
The active ingredients in feverfew include parthenolide and tanetin, and Feverfew also contains a relatively large amount of melatonin. The migraine-relieving activity of feverfew is believed to be due to parthenolide, an active compound that helps relieve smooth muscle spasms. In particular, it helps prevent the constriction of blood vessels in the brain. Parthenolide also inhibits the actions of compounds that cause inflammation and may inhibit cancer cell growth, parthenolide has also been found in 2005 to induce cell death in leukemia cancer stem cells. Feverfew has been used to calm red and irritated skin. Parthenolide also helps normalize the functions of platelets in the blood system by inhibiting platelet aggregation, reducing serotonin release from platelets and blocking the formation of PRO-inflammatory mediators.

1. Feverfew can prevent migraine headaches;
2. Feverfew can also reduce severity of migraine episodes;
3. Feverfew is also used to anti-inflammatory activity (may help arthritis);
4. Treat other painful disorders (stomach aches);
5. Treat menstrual irregularities.

Dosing:
A standard dose of feverfew should contain 0.2 to 0.7 percent of parthenolide. The University of Maryland Medical Center recommends taking 60 drops of the extract twice daily for symptoms associated with inflammation and arthritis. Feverfew extract also comes in capsule form. The recommended dose is 100 to 300 mg up to four times daily for migraine headaches. To ensure that you are taking the correct dose for your symptoms, read the product label carefully.

Application:

Feverfew extract can be used in food additives, beverages, supplements, pharmaceuticals, personal care & beauty products globally.

Safety:
Feverfew is safe and will not have any side effects for most people when used in the short term (four months). The study tested show that feverfew side effects include stomach upset, heartburn, diarrhea, constipation, bloating, flatulence, nausea, vomiting, etc. Other reported side effects include: tension, dizziness, headache, insomnia, stiff joints, fatigue, menstrual changes, rash, heavy heartbeat, weight gain.
There is no more than four months' use of feverfew safety studies.
Some people are chewing feverfew not swallow the tablets of feverfew (composed mainly of parthenolide in the medicinal feverfew extract). Chewing fresh feverfew leaves can cause mouth ulcers, loss of taste; swelling of the mouth, tongue and lips.

Special Precautions and warnings:
Pregnancy and breast-feeding women: pregnant and lactating women during pregnancy taking feverfew may be unsafe, may lead to early contractions and abortion. If you want to take, make sure under the guidance of a doctor .Best avoided if you are breast-feeding .
Allergy to ragweed and related plants: feverfew may cause allergic reactions to the Asteraceae class. Members of the Asteraceae including ragweed, chrysanthemums, marigolds, daisies and others. If you have allergies, be sure to check with your health care provider before taking feverfew.
Surgery: feverfew may reduce blood clotting, it may lead to intraoperative and postoperative bleeding.Stop taking feverfew at least 2 weeks before a scheduled surgery.