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Fucoidan

Latin Name:Phaeophyceae/brown algae
Active Ingredient:Fucoidan
CAS No:9072-19-9
Specification:60%,80%
MOQ:1kg
Lead Time:Within 7days after confirming order

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Fucoidan information:

Fucoidan is extract from the natural plant of Laminaria Japonica which is light grey to white powder after the special extract processing, we got the 60%-90% Fucoidan extract. They are powder form with good color. It’s mainly used for Medicine, cosmetic, food additive field as raw materials.

Fucoidan is a sulfated polysaccharide (MW: average 20,000) found mainly in various species of brown algae and brown seaweed such as mozuku, kombu, limu moui, bladderwrack, wakame, and hijiki (variant forms of fucoidan have also been found in animal species, including the sea cucumber). Fucoidan is used as an ingredient in some dietary supplement products.

Study of Fucodian powder:

There at least two distinct forms of fucoidan: F-fucoidan, which is >95% composed of sulfated esters of fucose, and U-fucoidan, which is approximately 20% glucuronic acid.

 

The physiological and biochemical effects of fucoidan have been examined in several small-scale in vitro and animal studies. F-fucoidan was reported to inhibit hyperplasia in rabbits and induce apoptosis in isolated human lymphoma cell lines in vitro. It has been hypothesized that these two effects may involve a common mechanism, but the evidence is inconsistent and no mechanism for the putative induction of apoptosis by fucoidan has been identified.A study in rats indicated that pre-treatment with fucoidan increases mortality subsequent to meningitis infection.[4] In a clinical study, orally-ingested Undaria-derived-fucoidan was reported to produce a small increase in the total number of CD34+ cells, and a more pronounced increase in the proportion of CD34+ cells that expressed CXCR4. The authors of the study hypothesized that the ability of fucoidan to mobilize hematopoetic cells with high levels of CXCR4 expression could be clinically valuable.
There at least two distinct forms of fucoidan: F-fucoidan, which is >95% composed of sulfated esters of fucose, and U-fucoidan, which is approximately 20% glucuronic acid.

 

The physiological and biochemical effects of fucoidan have been examined in several small-scale in vitro and animal studies. F-fucoidan was reported to inhibit hyperplasia in rabbits and induce apoptosis in isolated human lymphoma cell lines in vitro. It has been hypothesized that these two effects may involve a common mechanism, but the evidence is inconsistent and no mechanism for the putative induction of apoptosis by fucoidan has been identified.A study in rats indicated that pre-treatment with fucoidan increases mortality subsequent to meningitis infection.[4] In a clinical study, orally-ingested Undaria-derived-fucoidan was reported to produce a small increase in the total number of CD34+ cells, and a more pronounced increase in the proportion of CD34+ cells that expressed CXCR4. The authors of the study hypothesized that the ability of fucoidan to mobilize hematopoetic cells with high levels of CXCR4 expression could be clinically valuable.There at least two distinct forms of fucoidan: F-fucoidan, which is >95% composed of sulfated esters of fucose, and U-fucoidan, which is approximately 20% glucuronic acid.

There at least two distinct forms of fucoidan: F-fucoidan, which is >95% composed of sulfated esters of fucose, and U-fucoidan, which is approximately 20% glucuronic acid.

The physiological and biochemical effects of fucoidan have been examined in several small-scale in vitro and animal studies. F-fucoidan was reported to inhibit hyperplasia in rabbits and induce apoptosis in isolated human lymphoma cell lines in vitro. It has been hypothesized that these two effects may involve a common mechanism, but the evidence is inconsistent and no mechanism for the putative induction of apoptosis by fucoidan has been identified.A study in rats indicated that pre-treatment with fucoidan increases mortality subsequent to meningitis infection.In a clinical study, orally-ingested Undaria-derived-fucoidan was reported to produce a small increase in the total number of CD34+ cells, and a more pronounced increase in the proportion of CD34+ cells that expressed CXCR4. The authors of the study hypothesized that the ability of fucoidan to mobilize hematopoetic cells with high levels of CXCR4 expression could be clinically valuable.


Benefits:

1.Fucoidan has good anticoagulant activity

2. Inhibiting effect on the replication of several coated virus, such as human immunodeficiency and human cytomegalo—vims

3.Inhibiting the growth of cancer cells, it can also restrain the diffuse of tumor cells by enhancing immunit

4.Reduce the content of serum cholesterol and triglyceride. Besides, it has no such liver and kidney damage, or other side effects

5.Antidiabetics, radiation protection, antioxidant, the inhibition of heavy metal absorption fluctuate, and he restraint of mammals zona-binding combined


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